Status:
COMPLETED
Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
Lead Sponsor:
Medical University of Vienna
Conditions:
Meibomian Gland Dysfunction
Cataract
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The development of optical coherence tomography (OCT) and its application for in vivo imaging has opened entirely new opportunities in ophthalmology. The technology allows for both noninvasive visuali...
Eligibility Criteria
Inclusion
- For patients with meibomian gland dysfunction (MGD):
- MGD as evidenced by clinical features and gland expression (MGD Grading Scheme, Appendix I (Opitz, Harthan et al. 2015))
- For cataract patients:
- Cataract as evidenced from slit lamp examination, stage range between NII-NIII, CII-CIV, PII-PIII according to The Lens Opacity Classification System II (LOCS II) (Chylack, Leske et al. 1989) (Appendix II)
- For patients after minimally invasive glaucoma surgery (MIGS):
- Patients with history of MIGS secondary to glaucoma
- For patients with demodicosis:
- Demodicosis as evidenced from slit lamp examination and presence of Demodex confirmed by microscopic examination of the eye lashes (Liu, Sheha et al. 2010)
- For patients with conjunctival pathologies (cyst, naevus, pterygium):
- Conjunctival pathologies with a clinical diagnosis of the respective
- For patients with Acanthamoeba keratitis:
- Acanthamoeba keratitis as evidenced from slit lamp examination and confirmed by polymerase chain reaction (PCR) analysis of corneal epithelial and tear samples and culture isolation (Lehmann, Green et al. 1998)
- For aniridia patients:
- Anirida as evidenced from slit lamp examination
Exclusion
- Presence of any abnormalities preventing reliable measurements as judged by the investigator
- Pregnancy, planned pregnancy or lactating
Key Trial Info
Start Date :
July 12 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 16 2023
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT03461978
Start Date
July 12 2017
End Date
June 16 2023
Last Update
May 23 2025
Active Locations (1)
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1
Medical University Vienna, Department of Clnical Pharmacology
Vienna, Vienna, Austria, 1090