Status:
UNKNOWN
The ENIGMA Study: Eastern Inflammatory Bowel Disease Gut Microbiota
Lead Sponsor:
Chinese University of Hong Kong
Collaborating Sponsors:
University of Melbourne
The University of Queensland
Conditions:
Crohn Disease
Eligibility:
All Genders
18+ years
Brief Summary
The incidence of inflammatory bowel diseases, (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), is increasing in the developing world. Our recent Asia-Pacific population-based study in...
Detailed Description
The incidence of inflammatory bowel diseases, (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), is increasing in the developing world. Our recent Asia-Pacific population-based study in...
Eligibility Criteria
Inclusion
- aged ≥18 years old
- competent to provide informed consent (no mental illness or dementia, etc. that will hinder the understanding)
- living in the same area for recent 6 months
Exclusion
- Use of anticoagulants within 1 week
- Use of prebiotics, probiotics or antibiotics in recent 3 months
- Use of laxatives or "Stoppers" in the last 3 months
- Vaccination within 3 months
- Recent dietary changes (e.g. becoming vegetarian/vegan)
- Known complex infections or sepsis (excl. simple infections such as influenza etc.)
- Known history or concomitant significant food allergies
- Known history of severe organ failure (including decompensated cirrhosis, malignant disease, kidney failure, epilepsy, active serious infection, acquired immunodeficiency syndrome)
- Bowel surgery in the last 6 months (excluding colonoscopy/ procedure related to perianal disease)
- Having stoma
- Known pregnancy
- Travel history within 4 weeks (need to define the travel history in China)
- Known contraindications to colonoscopy
- Colonoscopy in the last month prior to sampling
Key Trial Info
Start Date :
August 29 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2024
Estimated Enrollment :
532 Patients enrolled
Trial Details
Trial ID
NCT03462875
Start Date
August 29 2018
End Date
February 28 2024
Last Update
February 8 2023
Active Locations (1)
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1
Prince of Wales Hospital
Hong Kong, Hong Kong