Status:
UNKNOWN
Identification of EMT Indicators in Healthy and Periodontally Diseased Gingival Samples
Lead Sponsor:
Cairo University
Conditions:
Chronic Periodontitis
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The current study focuses on the localization and quantitative assessment of growth factors and cytokines related to the EMT process found in the human gingival tissue samples taken from periodontally...
Detailed Description
In a case control human study The existence and the amount of the indicators and cytokines for EMT in the gingival tissue samples taken from the periodontitis patients will be investigated and compare...
Eligibility Criteria
Inclusion
- Inclusion criteria for healthy group:
- Absence of any clinical sign of gingival inflammation
- Probing depth ≤3 mm
- No clinical attachment loss.
- Inclusion criteria for periodontitis group:
- Generalized presence of clinical signs of gingival inflammation
- Generalized probing depth ≥4 mm
- Generalized clinical attachment loss of ≥2 mm.
Exclusion
- • Patients with any systemic disease,
- Smokers
- Pregnant or lactating women,
- Cervical/proximal/subgingival caries or restorations,
- Periodontal or antimicrobial therapy within 3 months before sampling.
Key Trial Info
Start Date :
April 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 15 2019
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT03462953
Start Date
April 15 2018
End Date
March 15 2019
Last Update
March 13 2018
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