Status:
UNKNOWN
Analysis of Bone Micro-Architecture as a Clinical Biomarker for Image-Based Fracture Risk Estimation.
Lead Sponsor:
State University of New York - Upstate Medical University
Conditions:
Osteoporosis
Eligibility:
FEMALE
60+ years
Phase:
NA
Brief Summary
Osteoporosis is a common disease among elderly people, which leads to an increased bone fracture risk. Bone fractures can greatly reduce quality of life and increase age-related problems including red...
Detailed Description
Osteoporosis is a common disease among elderly people, the progression of which leads to an increased bone fracture risk, which can adversely affect quality of life and increase age-related morbidity/...
Eligibility Criteria
Inclusion
- Age 60 or greater Caucasian female with confirmed osteoporosis via prior DEXA.
- Patients with known vertebral fractures (Genant Grade 2 or higher) and with no fractures (Genant Score \<2) from prior DEXA/VFA analysis will be recruited.
- Patients with fractures must have at least one lumbar vertebral body with no fracture(s) (as seen on prior DEXA scan) for analysis.
Exclusion
- Incidental finding to include pathology unrelated to osteoporosis that would directly affect bone architecture in the L spine (e.g. lytic bone lesions)
- Study DEXA scan reveals all lumbar vertebra have fractures (Genant \>= 2)
- Orthopedic hardware in the lumbar spine region
- Unable to have a CT scan (e.g. too heavy for CT scan table, 660 lb. limit)
Key Trial Info
Start Date :
June 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03463850
Start Date
June 1 2016
End Date
November 30 2023
Last Update
November 19 2021
Active Locations (1)
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1
SUNY Upstate Medical University
Syracuse, New York, United States, 13210