Status:

COMPLETED

Clinical Trial Comparing Two Bladder Instillations for IC/BPS

Lead Sponsor:

Olivia Cardenas-Trowers, M.D.

Conditions:

Interstitial Cystitis

Bladder Pain Syndrome

Eligibility:

FEMALE

18+ years

Phase:

PHASE3

Brief Summary

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a condition that results in long-term bladder and pelvic pain. IC/BPS affects women more often than men. How the disorder develops is not comple...

Detailed Description

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic pain disorder involving the genitourinary tract. IC/BPS disproportionately affects women with over 80% of patients with IC/BPS as fema...

Eligibility Criteria

Inclusion

  • Women 18 years and older
  • Women with IC/BPS who have a score of ≥ 6 on either index (problem or symptom index) of the O'Leary-Sant questionnaire who have selected bladder instillations as part of their IC/BPS treatment
  • Suitability for follow-up

Exclusion

  • Contraindications and/or allergies to the ingredients used in the bladder instillations
  • Diagnosis of idiopathic thrombocytopenic purpura
  • Does not desire to undergo bladder instillation therapy or unwilling to undergo bladder instillation therapy on schedule mandated by study
  • Have a known alternative diagnosis explaining bladder pain symptoms that would preclude the diagnosis of IC/BPS (e.g. radiation cystitis, active urinary tract infection with bacteria or fungus treated within last 2 weeks or diagnosed at index visit, bladder injury or trauma within the last 30 days)
  • Inability to speak or read English
  • Bladder instillation within the past 4 weeks

Key Trial Info

Start Date :

January 25 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 23 2020

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03463915

Start Date

January 25 2019

End Date

October 23 2020

Last Update

September 1 2021

Active Locations (1)

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1

University of Louisville Urogynecology at Springs Medical Center

Louisville, Kentucky, United States, 40205