Status:

COMPLETED

Influence of Respiratory Gases Conditioning on Aerosol Delivery During Invasive Ventilation

Lead Sponsor:

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Conditions:

Brain Injuries, Traumatic

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The intention is to enroll a specific sample of intubated patients. To compare the effect of respiratory gas conditioning on lung deposition and considering the well-known influences of lung pathology...

Eligibility Criteria

Inclusion

  • Aged 18 years or older
  • Postoperative neurosurgery intubated patients admitted for brain neurosurgery in the ICU (Intensive care neuro-traumatologic and Toxicologic)- With a healthy lung function.
  • Signed and dated informed consent should be obtained in accordance of local regulations.

Exclusion

  • Spine neurosurgery
  • History of cardiovascular and pulmonary disease
  • Extubation immediately after surgery
  • Modification of the allocated humidification technique before or during the nebulization (heated-humidifier deficiency or safety concern)
  • Inaccurate quantification of aerosol deposition (i.e., artifacts or overlap of tracheal and pulmonary deposition).

Key Trial Info

Start Date :

January 22 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2020

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT03464175

Start Date

January 22 2018

End Date

December 15 2020

Last Update

November 4 2022

Active Locations (1)

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1

Cliniques Universiataires Saint-Luc

Brussels, Belgium, 1200

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