Status:

UNKNOWN

Evaluation of Stress Sensitivity and Hyperemotivity in Epilepsy Compared to and a Group of Healthy Volunteers

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Epilepsy

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Recently, a possible subtype of temporal lobe epilepsy (TLE) has been proposed: this subtype presents ipsilateral amygdala enlargement (AE) without any other lesion. However, little is known about its...

Detailed Description

TLE-AE could concern 16 to 64 % of the TLE with "negative" MRI (Beh et al., 2016). TLE-AE patients may suffer from anxiety and depression (Lv et al, 2014). In clinical practice, it has been also iden...

Eligibility Criteria

Inclusion

  • \- For all epileptic patients: Age between 18 and 65. Epilepsy (TLE or not) followed by an epileptologist.
  • \- For TLE-AE: An AE identified on the MRI by an expert neuroradiologist. MRI must be less than one year.
  • \- For non AE epileptic patients: No AE reported in the MRI by an expert neuroradiologist.

Exclusion

  • Any mental disorder.
  • Any diabetes
  • Beta-blockers
  • Neuroleptics
  • Any neurologic diseases for the healthy volunteers.

Key Trial Info

Start Date :

March 8 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2020

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03464370

Start Date

March 8 2018

End Date

March 1 2020

Last Update

July 20 2018

Active Locations (1)

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1

University Hospital Toulouse

Toulouse, France, 31059