Status:
COMPLETED
The Influence of Hypotensive Drugs on Mineral Status in Experimental and Clinical Studies
Lead Sponsor:
Poznan University of Life Sciences
Collaborating Sponsors:
Poznan University of Medical Sciences
Conditions:
Nutritional Disorder
Hypertension
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The aim of the study was to evaluate the effects of hypotensive treatment combined with a higher zinc supply in the diet and supplements on the mineral status and selected biochemical parameters of ne...
Detailed Description
The study was designed as a prospective randomized trial and was performed in three stages. In the first stage, primary hypertension was diagnosed and antihypertensive monotherapy was implemented. In ...
Eligibility Criteria
Inclusion
- informed written consent;
- age 18-65 years;
- primary hypertension;
- beginning monotherapy with an antihypertensive drug;
- stable body weight (less than 3 kg self-reported change during the three months prior to enrollment).
Exclusion
- any secondary form of hypertension;
- the use of mineral supplements within the three months prior to enrollment;
- lipid disorders requiring treatment in the three months prior to the trial;
- a history of ischemic heart disease, stroke, congestive heart failure,
- clinically significant arrhythmia or conduction disorders, peripheral artery or vein disease, diabetes mellitus, abnormal renal, liver or thyroid gland function,
- clinically significant chronic or acute inflammatory process within the respiratory, genitourinary, or digestive tract, or in the oral cavity, larynx, pharynx, or in the paranasal sinuses, or connective tissue diseases, arthritis, or malignancy;
- infection in the month prior to enrollment,
- having an pacemaker implanted;
- alcohol, nicotine or drug abuse;
- mental disorders;
- pregnancy, childbirth or lactation at enrollment or in the three months prior to enrollment;
- or any other condition that, in the opinion of investigators, would make participation in the study not in the best interest of the subject, or could prevent, limit, or confound the efficacy of the study.
Key Trial Info
Start Date :
January 2 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2016
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT03465462
Start Date
January 2 2016
End Date
December 30 2016
Last Update
March 14 2018
Active Locations (1)
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1
Poznan University of Life Sciences
Poznan, Poland, 60-624