Status:

UNKNOWN

Cytomegalovirus Infection in Steroid-refractory Ulcerative Colitis

Lead Sponsor:

Dr mohammedRmadan hamad

Collaborating Sponsors:

Assiut University

Conditions:

Cmv Colitis

Eligibility:

All Genders

18-75 years

Brief Summary

Aim of the work * To identify the prevalence of CMV infection in patients with steroid-refractory ulcerative colitis. * To assess the clinical and endoscopic conditions in these patients.

Detailed Description

Ulcerative colitis (UC) is a chronic inflammatory disorder of the colonic mucosa characterized by recurrent attacks of bloody diarrhea, abdominal cramping and mucosal ulceration that often requires lo...

Eligibility Criteria

Inclusion

  • All eligible patients have an established diagnosis of ulcerative colitis, including clinical, endoscopic and histologic assessments. Eligible patients have moderately to severely active disease (total Mayo score, 6 - 12 points), with endoscopy subscore of at least 2 and had inadequate response to or cannot tolerate treatment with at least one of the following: corticosteroids and/or azathioprine or 6-mercaptopurine and/or 5-aminosalicylate-containing medications.

Exclusion

  • \- Patients with remittent UC
  • Patients known to have IBD other than ulcerative colitis

Key Trial Info

Start Date :

August 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2019

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03467841

Start Date

August 1 2018

End Date

September 1 2019

Last Update

March 19 2018

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