Status:

UNKNOWN

Contrast-enhanced Diffusion-weighted MRI to Detect Liver Metastases in Patients With Pancreatic Cancer

Lead Sponsor:

Radboud University Medical Center

Collaborating Sponsors:

Dutch Cancer Society

Conditions:

Pancreatic Neoplasms

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Given the dismal prognosis of pancreatic cancer, detecting liver metastases early can avoid inappropriate therapy with the associated substantial risks, long-term hospital admissions and high costs, b...

Eligibility Criteria

Inclusion

  • 18 years and older
  • clinical suspicion of pancreatic cancer
  • written (signed and dated) informed consent

Exclusion

  • previous treatment for pancreatic cancer (e.g. chemotherapy, radiotherapy, surgery, ablation therapy)
  • concomitant malignancies, except for adequately treated basocellular carcinoma of the skin or in situ carcinoma of the cervix uteri. Subjects with prior malignancies must be disease-free for at least 5 years
  • contra-indications to undergo CT (due to e.g. extreme claustrophobia, untreatable contrast allergy, renal function impairment)
  • contra-indications to undergo MRI (due to e.g. claustrophobia, untreatable contrast allergy, or not MRI compatible medical devices)
  • insufficient command of the Dutch language to be able to understand the patient information or fill in the questionnaires
  • pregnancy

Key Trial Info

Start Date :

December 22 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2023

Estimated Enrollment :

465 Patients enrolled

Trial Details

Trial ID

NCT03469726

Start Date

December 22 2017

End Date

January 1 2023

Last Update

September 21 2021

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Konstantopouleio general hospital

Athens, Greece

2

Radboudumc

Nijmegen, Gelderland, Netherlands, 6525GA

3

Jeroen Bosch Ziekenhuis

's-Hertogenbosch, Netherlands, 5223 GZ

4

Medisch Spectrum Twente

Enschede, Netherlands, 7512KZ