Status:
COMPLETED
Interaction Between NGF and Acute Exercise-induced Ischemia
Lead Sponsor:
Aalborg University
Conditions:
Hyperalgesia
Pain Response
Eligibility:
All Genders
18-55 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to investigate pain evoked responses and facilitation of NGF-induced mechanical muscle hyperalgesia over time following an acute exercised-induced ischemic condition in a ...
Detailed Description
Assessing evoked pain responses and muscle hyperalgesia following contractions during acute ischemia in a NGF-sensitized muscle may clarify whether an interaction between NGF sensitization and acidic ...
Eligibility Criteria
Inclusion
- Healthy and pain free volunteers
Exclusion
- Pregnancy
- Drug addiction defined as the use of cannabis, opioids or other drugs
- Previous neurologic, mental illnesses, or psychiatric diseases.
- Past history of chronic pain in the musculoskeletal system (muscle, joint, cartilage, connective tissue)
- Participation in other pain trials throughout the study period
- Lack of ability to cooperate
- Taking any analgesic 24 hours before the injections
- Performing any strenuous leg exercise through out the study period causing sore muscles
Key Trial Info
Start Date :
March 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 15 2018
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT03470038
Start Date
March 15 2018
End Date
June 15 2018
Last Update
February 15 2019
Active Locations (1)
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1
Aalborg University
Aalborg, Denmark, 9220