Status:

UNKNOWN

The Comparison Between Traditional Laparoscopy-assisted Surgery and NOSES in Radical Resection of Colorectal Cancer

Lead Sponsor:

Dong Yang

Conditions:

Laparoscopy-assisted Surgery

Total Laparoscopic Surgery With no Incision (Natural Orifice Transluminal Endoscopic Surgery, NOSES)

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

This study is to compare the short-term and long-term outcomes of traditional laparoscopy-assisted surgery and total laparoscopic surgery with no incision (natural orifice transluminal endoscopic surg...

Eligibility Criteria

Inclusion

  • All cases should be diagnosed as rectal or sigmoid colon cancer by histology or cytology. The tumor is 5-20cm from the pectinate line. The clinical stage is T1-2, N0, M0 for rectal cancer and T1-T3, N0-2, M0 for sigmoid colon cancer.
  • Eastern Cooperative Oncology Group (ECOG) scale 0-2
  • Heart, lung, liver, and kidney function can tolerate operation
  • Patients and their families are able to understand and be willing to participate in this clinical study and to sign informed consent.

Exclusion

  • history of colorectal malignant disease
  • recent diagnosis of other malignant tumors (except for papillary carcinoma of the thyroid gland and basal cell carcinoma of the skin)
  • patients with intestinal obstruction, intestinal perforation, bleeding requiring emergency surgery
  • a history of abdominal surgery (which makes it difficult to perform laparoscopic procedures), severe systemic disease such as diabetes, severe chronic lung disease, cirrhosis, other malignant diseases
  • combined colorectal multiple carcinomas
  • poor anal function before operation and incontinence of defecation
  • with a history of serious mental illness
  • pregnant or lactating women
  • The researchers believe that the patients are unsuitable to participate in the researchers with other cases. A patient or family refusal to join

Key Trial Info

Start Date :

March 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 20 2022

Estimated Enrollment :

158 Patients enrolled

Trial Details

Trial ID

NCT03470142

Start Date

March 20 2018

End Date

March 20 2022

Last Update

September 24 2019

Active Locations (1)

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1

the First Hospital of Jilin University

Ch’ang-ch’un, Jilin, China, 130021