Status:
UNKNOWN
Isotretinoin In Preventing Recurrences In Chronic Recurrent Dermatophytosis
Lead Sponsor:
Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions:
Tinea
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This study is a prospective, double blinded, randomized, pilot study to assess the effectiveness of oral low dose isotretinoin in combination with oral terbinafine and itraconazole in preventing recur...
Detailed Description
Over the last couple of years, the major concern in dermatophytic infections has been the occurrence of recurrent infections. This, in spite of the patients being treated with gold standard drugs, nam...
Eligibility Criteria
Inclusion
- • All patients with chronic recurrent dermatophytosis of more than 6 months duration who have been adequately treated for every episode still developing recurrences within one month of stopping oral antifungal drugs.
Exclusion
- Patients with contraindications to receiving oral terbinafine, itraconazole or isotretinoin like those suffering from congestive cardiac failure, cardiac arrhythmias, liver or kidney function impairment or are on drugs whose plasma concentrations are likely to be increased by the concurrent administration of oral itraconazole.
- Pregnancy and lactation.
- Patients on immunosuppressive drugs.
- Immunocompromised patients (HIV positive/renal transplant etc).
Key Trial Info
Start Date :
April 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2019
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03471455
Start Date
April 1 2018
End Date
January 1 2019
Last Update
May 1 2018
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.