Status:

COMPLETED

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

Lead Sponsor:

University of California, San Diego

Conditions:

Sedentary Lifestyle

Eligibility:

FEMALE

55+ years

Phase:

NA

Brief Summary

Epidemiological findings indicate that older adults do not meet physical activity (PA) guidelines \& spend up to 11 hrs/day sitting. Given the high prevalence of sedentary behavior (SB), the higher ch...

Detailed Description

Primary Aims: In our primary biomarker outcomes of glucose regulation (fasting insulin \& glucose, HbA1c, HOMA-IR) \& blood pressure (BP): 1. Investigate the 12 week effects of increased standing an...

Eligibility Criteria

Inclusion

  • Female;
  • 55 years of age and above;
  • any ethnicity or race;
  • screened to sit for 7 or more hours per day, perform less than 70 sit-to-stand transitions per day
  • ambulatory;
  • medically stable without any health conditions that would inhibit standing or PA;
  • able to give informed consent \& comply with study protocols;
  • able to read and write fluently in English;
  • able to travel to study visits; and
  • no menstruation for at least one year;
  • BMI 25-45
  • able to walk, stand and transition without high risk of falling.

Exclusion

  • Male;
  • younger than 55 years of age;
  • sit for less than 7 hours per day, perform 71 or more sit-to-stand transitions per day
  • mental state that would preclude complete understanding of the protocol or compliance;
  • physical limitations to completing any of the study conditions;
  • menstruation less than one year prior;
  • unable to complete the Short Physical Performance Battery,
  • Active cancer
  • body Mass Index \<25 or \>45kg/m2,
  • use of insulin

Key Trial Info

Start Date :

May 30 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2024

Estimated Enrollment :

407 Patients enrolled

Trial Details

Trial ID

NCT03473145

Start Date

May 30 2018

End Date

December 31 2024

Last Update

November 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UC San Diego

La Jolla, California, United States, 92093