Status:
COMPLETED
Functional Connectivity & Stimulation-enhanced Therapy Post Stroke
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
National Institute of General Medical Sciences (NIGMS)
University of Delaware
Conditions:
Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
After stroke, it is common for individuals to experience hand impairment. This deficit can severely restrict functional ability and independence. Recovery of hand function following stroke is highly v...
Detailed Description
The ability to predict individuals' responses to treatment can enable effective allocation of a treatment to likely responders. The long-term goal is to determine whether acute changes in brain functi...
Eligibility Criteria
Inclusion
- Age = 18 or older
- At least 6 months post-stroke
- Moderate upper limb impairment with the ability to participate in hand task practices
- Fingertip touch sensory deficits (e.g., Monofilament\>2.83, 2-point discrimination\>5mm, sense of numbness, tingling)
Exclusion
- Complete upper limb deafferentation
- Rigidity (Modified Ashworth Scale=5)
- Botulinum toxin injection within 3 months prior to enrollment or during enrollment
- Brainstem stroke
- Comorbidity (peripheral neuropathy, orthopaedic conditions in the hand that limit ranges of motion, premorbid neurologic conditions, compromised skin integrity of the hand/wrist due to long-term use of blood thinners)
- Concurrent upper extremity rehabilitation therapy
- Language barrier or cognitive impairment that precludes following instructions or providing consent
- MRI incompatible.
Key Trial Info
Start Date :
March 7 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 24 2018
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT03473808
Start Date
March 7 2018
End Date
September 24 2018
Last Update
March 5 2019
Active Locations (1)
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1
Medical University of South Carolina
Charleston, South Carolina, United States, 29403