Status:
UNKNOWN
Prospective Genetic Study in Patients With Ovarian Insufficiency
Lead Sponsor:
The First Affiliated Hospital of Anhui Medical University
Collaborating Sponsors:
National Research Institute for Family Planning, China
Conditions:
Premature Ovarian Failure
Primary Ovarian Insufficiency
Eligibility:
FEMALE
Brief Summary
genetic screening and etiological analysis was conducted on patients with ovarian insufficiency and decline in ovarian reserve. All patients were enrolled in the IVF-treated and non-IVF-treated groups...
Detailed Description
The cause of ovarian insufficiency and decline in ovarian reserve are not clear, but most researchers think the probable causes are mainly three aspects: chromosomal abnormalities, genetic factors and...
Eligibility Criteria
Inclusion
- Patients diagnosed as "premature ovarian insufficiency", "diminished ovarian reserve", "primary amenorrhea", " ovarian dysgenesis", " repeated implantation failure"
Exclusion
- To rule out polycystic ovary syndrome（PCOS）, iatrogenic factors (such as surgery, radiotherapy and chemotherapy, etc.) lead to premature ovarian insufficiency in patients
Key Trial Info
Start Date :
April 20 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 24 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03474120
Start Date
April 20 2018
End Date
December 24 2023
Last Update
February 21 2021
Active Locations (1)
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1
Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China, 230032