Status:

COMPLETED

Program for African American Cognition & Exercise

Lead Sponsor:

Pennington Biomedical Research Center

Collaborating Sponsors:

BrightFocus Foundation

Conditions:

Aging

Eligibility:

All Genders

65-85 years

Phase:

NA

Brief Summary

The study is designed to develop and evaluate a physical activity promotion program among elderly African Americans with a long-term goal of reducing risk of Alzheimer's disease. The motivation for th...

Detailed Description

Investigators will randomize 56 older African American adults into 1) a physical activity intervention specifically tailored to older African American or 2) a successful aging group. The 12-week physi...

Eligibility Criteria

Inclusion

  • 65 - 85 years of age
  • African American
  • sedentary or insufficiently active
  • not cognitively impaired
  • physically capable of exercise
  • willing to accept randomization
  • willing to attend group sessions
  • willing to live in the study area for the next 6 months
  • willing to allow researchers to use data for research purposes after study participation is completed
  • free of conditions that would make regular exercise unsafe as deemed by the medical investigator

Exclusion

  • unable or unwilling to give informed consent or accept randomization in either study group
  • are cognitively impaired (MMSE score of ≤ 26)
  • are unable to complete physical activity requirements (SPPB ≤ 3, complete 2 minute walk without sitting or resting against a surface)
  • are too active (steps per day \> 50th percentile for age and gender)
  • have uncontrolled hypertension (systolic blood pressure \> 200 mmHg and/or diastolic blood pressure \> 110 mmHg).
  • gave had a hip fracture, hip or knee replacement, or spinal surgery in the past 6 months
  • have had a myocardial infarction, major heart surgery (i.e., valve replacement or bypass surgery), stroke, deep vein thrombosis or pulmonary embolus in the past 6 months
  • are undergoing physical therapy or cardiopulmonary rehabilitation
  • are currently enrolled in another randomized trial involving lifestyle or pharmaceutical interventions
  • have another member of the household that is a participant in PAACE
  • have plans to relocate out of the study area within the next 6 months
  • have uncontrolled diabetes that in the judgment of the MI may interfere with study participation
  • have other medical, psychiatric, or behavioral factors that in the judgment of the Principal or Medical Investigator may interfere with study participation or the ability to follow the intervention protocol

Key Trial Info

Start Date :

February 19 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2019

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT03474302

Start Date

February 19 2018

End Date

June 30 2019

Last Update

June 25 2020

Active Locations (1)

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1

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States, 70808