Status:
COMPLETED
Sodium Chloride and Contrast Nephropathy
Lead Sponsor:
Hospital Universitario Ramon y Cajal
Collaborating Sponsors:
Instituto de Salud Carlos III
Ministerio de Sanidad, Servicios Sociales e Igualdad
Conditions:
Kidney Failure, Chronic
Kidney Failure, Acute
Eligibility:
All Genders
65+ years
Phase:
PHASE2
Brief Summary
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast. Patients wi...
Detailed Description
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast. Patients wi...
Eligibility Criteria
Inclusion
- Patients \>65 years,
- Both sexes,
- With at least one of the following criteria: diabetes or stable heart failure or chronic kidney disease (estimated glomerular filtration rate between 30 and 60 ml/min),
- Undergoing CT scan with contrast
- Written informed consent.
Exclusion
- Estimated glomerular filtration rate \<30 ml/min,
- Serum potassium \<3.5 mEq/L,
- Infusion of iodine contrast in the previous 15 days,
- Administration of nephrotoxic drugs in the previous 72 hours or expected in the following hours after contrast infusion,
- Decompensated chronic conditions (heart failure, chronic obstructive pulmonary disease, hypertension),
- Allergy to iodine contrast,
- Presence of hyperchloremia or hypernatremia.
Key Trial Info
Start Date :
April 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 29 2019
Estimated Enrollment :
271 Patients enrolled
Trial Details
Trial ID
NCT03476460
Start Date
April 1 2014
End Date
November 29 2019
Last Update
March 20 2025
Active Locations (1)
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1
Hospital Universitario Ramon y Cajal
Madrid, Spain, 28034