Status:
UNKNOWN
Effects of Different Types of Physical Training in Patients With Pulmonary Arterial Hypertension.
Lead Sponsor:
University of Nove de Julho
Collaborating Sponsors:
University of Miami
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Conditions:
Pulmonary Arterial Hypertension
Cardiovascular Diseases
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
Although there has been some progress in pharmacological management of PAH, limited functional capacity and low survival still persist, but there is evidence that exercise training can be accomplished...
Detailed Description
Pulmonary arterial hypertension (PAH) is characterized by pathological changes in the pulmonary vasculature which cause an increase in pulmonary vascular resistance (PVR), restricting the flow of bloo...
Eligibility Criteria
Inclusion
- Having confirmed diagnosis of PAH, based on elevated pressure in the pulmonary artery measured by catheterization of the heart at rest, with WHO functional (World Health Organization's - Functional Assessment for Pulmonary Hypertension - modified after New York Heart Association Functional Classification (NYHA) functional classification) classes I, II, III or IV to capture PAH patients with pré-capillary involvement;
- Clinically stable with no previous hospitalizations in the last four weeks;
- Receiving PAH specific drug therapy for at least 3 months before the study began.
Exclusion
- Use of continuous oxygen therapy;
- Significant musculoskeletal disease or pain / claudication members;
- Neurologic or cognitive impairment, psychiatric disorders or psychological mood (making it difficult for patients to understand the required tests);
- History of moderate or severe chronic lung disease;
- PAH patients with post-capillary involvement.
- Cardiac disease associated with cardiac failure, angina and / or unstable heart rhythm.
Key Trial Info
Start Date :
January 10 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 10 2020
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03476629
Start Date
January 10 2016
End Date
December 10 2020
Last Update
November 4 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Santa Casa de São Paulo Hospital
São Paulo, São Paulo, Brazil