Status:

UNKNOWN

Exposure of NICU Patients to PVC Plasticizers in At-risk Clinical Situation: Biomonitoring Study From Urinary Samples

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Neonates or Premature Babies

Patient With Urinary Catheter

Eligibility:

All Genders

1-18 years

Brief Summary

In response to restrictions related to the use of DEHP as a plasticizer for PVC medical devices (MDs), manufacturers have resorted to alternative plasticizers. These are now integrated into many MDs s...

Detailed Description

The purpose of this biomonitoring study consists to evaluate the exposure of newborns and premature babies hospitalized in NICU to these plasticizers (DEHT and TOTM), by qualitative and quantitative m...

Eligibility Criteria

Inclusion

  • hospitalized minor patient in NICU
  • hospitalized patient in one of the planned services of the study- hospital stay provided for inclusion ≥ 48 hours
  • patient with a urinary catheter at the time of inclusion in the study
  • patient undergoing during the stay at least 1 of the following medical procedures: enteral nutrition, parenteral nutrition, extra-renal purification, ECMO, transfusion, lipid infusion, plasmapheresis
  • patient whose parents have expressed their non-opposition to his participation in the study

Exclusion

  • death of the patient
  • leaving hospital
  • patient becoming anuric (diuresis \<1mL / kg / h for more than 24 hours) under study

Key Trial Info

Start Date :

February 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2019

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03477409

Start Date

February 1 2018

End Date

January 31 2019

Last Update

March 30 2018

Active Locations (1)

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CHU Clermont-Ferrand

Clermont-Ferrand, France, 63003