Status:
COMPLETED
Advanced Monitoring to Inform and Guide Perioperative Hemodynamic Optimization 1 (AMIGO-1) Study
Lead Sponsor:
University Health Network, Toronto
Conditions:
Intraoperative Fluid Management
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Serious complications occur in about 16% of major surgeries. Episode of hypotension during surgery may be a leading cause of these complications. Even though hypotension occurs frequently during surge...
Eligibility Criteria
Inclusion
- Age ≥40 years
- Abdominal, retroperitoneal, pelvic or vascular surgery requiring general anesthesia and planned postoperative stay of ≥48 hours for medical reasons
- Elevated perioperative cardiovascular risk based on at least one of the following:
- cardiovascular comorbidities: coronary artery disease, heart failure, cerebrovascular disease, or peripheral arterial disease
- elevated age (≥70 y),
- smoker,
- hypertension,
- diabetes mellitus,
- or preoperative estimated glomerular filtration rate ≤60mL/min/1.73m2
- Planned placement of invasive arterial line for clinical care
Exclusion
- Preoperative dialysis dependence
- Minimally invasive procedures (i.e., laparoscopic or endovascular approach)
- Intra-thoracic procedures
- Non-sinus rhythm
- Liver resection surgery
Key Trial Info
Start Date :
May 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03477617
Start Date
May 3 2018
End Date
September 1 2019
Last Update
September 29 2020
Active Locations (1)
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1
Toronto General Hospital, University Health Network
Toronto, Ontario, Canada, M5G 2C4