Status:
UNKNOWN
The Role of the Muscle-nervous System Interface in Cancer Cachexia
Lead Sponsor:
University of Roma La Sapienza
Conditions:
Cachexia; Cancer; Sarcopenia
Eligibility:
All Genders
18-100 years
Brief Summary
Sarcopenia is an important component of cachexia associated with cancer, and their high incidence in cancer patients emphasizes the need for a better understanding of its mechanisms, which can result ...
Detailed Description
The agrin is a protein that acts on neuromuscular junctions (NMJs) promoting stabilization of same, which results in the maintenance and growth of muscle fibers, but the cleavage of agrin, a process b...
Eligibility Criteria
Inclusion
- cancer diagnosis
Exclusion
- continuously use of anti-inflammatory medications;
- present renal and/or liver failure,
- AIDS,
- inflammatory bowel disease or chronic inflammatory processes not related to cachexia.
Key Trial Info
Start Date :
March 16 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03477721
Start Date
March 16 2018
End Date
April 30 2018
Last Update
March 26 2018
Active Locations (1)
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1
Department of Clinical Medicine, Sapienza University of Rome
Rome, Italy, 00185