Status:
UNKNOWN
Culprit Lesions in NSTEMI With Multi Vessel Disease (NSTEMI-CULPRIT)
Lead Sponsor:
Rigshospitalet, Denmark
Conditions:
NSTEMI - Non-ST Segment Elevation MI
Multi Vessel Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
Acute myocardial infarction owes to a plaque rupture resulting in total (STEMI) or partial occlusion (NSTEMI) of the coronary artery. In patients with a partial occlusion and multi vessel disease (MVD...
Detailed Description
Background Acute myocardial infarction owes to a plaque rupture resulting in total (STEMI) or partial occlusion (NSTEMI) of the coronary artery. Current guidelines in NSTEMI recommend an invasive cor...
Eligibility Criteria
Inclusion
- Patients \> 18 years of age
- NSTEMI (ECG changes and/or troponin/creatine kinase myocardial band (CK-MB) rise) within 48 hours after symptom debut.
- Multivessel disease at CAG: More than one vessel with \>50% stenosis.
Exclusion
- Known intolerance of heparin or contrast medium.
- Inability to understand information or to provide informed consent.
- estimated glomerular filtration rate (eGFR) \< 30 ml/min.
- Other reasons for troponin rise not applicable to acute myocardial infarction.
- Atrial fibrillation at admission.
- Patients with contraindication for CMR will only have OCT performed.
- Potential pregnancy
- Unstable patients requiring acute CAG and PCI
Key Trial Info
Start Date :
January 10 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03479593
Start Date
January 10 2018
End Date
January 1 2024
Last Update
March 29 2023
Active Locations (1)
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1
Rigshospitalet
Copenhagen, Denmark, 2100