Status:

COMPLETED

Effects of a PF Ophthalmic Solution Containing HA0.4% and TAU 0.5%

Lead Sponsor:

Fondazione G.B. Bietti, IRCCS

Conditions:

Glaucoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Eligible patients underwent evaluation of ocular surface parameters by Ocular Surface Disease Index (OSDI) and Glaucoma Symptom Scale (GSS) questionnaires, Break Up Time test (BUT), Schirmer I test, c...

Detailed Description

At the screening visit all patients underwent comprehensive ophthalmological examination including best corrected visual acuity assessment, slit lamp evaluation, IOP measurement using Goldmann applana...

Eligibility Criteria

Inclusion

  • Diagnosis of glaucoma with an ongoing topical therapy with two or more preserved ocular hypotensive eye-drops per day for at least two years.

Exclusion

  • Best corrected visual acuity ≤ 20/40
  • History of active or past ophthalmological diseases different than glaucoma
  • Contraindications to use of topical solution components used in this study
  • Current use of contact lenses
  • Current use or use in the past 6 months of ocular medications other than hypotensive eye-drops
  • Systemic treatments known to affect tear secretion
  • Any history or slit lamp evidence of eye surface diseases different from dry eye
  • History of ocular trauma
  • Surgery or laser treatments
  • Rheumatologic and autoimmune diseases
  • Diabetes
  • Peripheral neuropathies
  • Use of systemic steroids or immunosuppressants

Key Trial Info

Start Date :

December 19 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 27 2017

Estimated Enrollment :

39 Patients enrolled

Trial Details

Trial ID

NCT03480295

Start Date

December 19 2016

End Date

April 27 2017

Last Update

March 29 2018

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