Status:

COMPLETED

Monitoring the IMmUological TOXicity of Drugs

Lead Sponsor:

Groupe Hospitalier Pitie-Salpetriere

Collaborating Sponsors:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Arthritis

Systemic Lupus Erythematosus

Eligibility:

All Genders

18+ years

Brief Summary

Several drugs and chemotherapies seem to have an impact on the immunological system. This study investigates reports of immunological toxicities, including the International classification of disease ...

Detailed Description

Several drugs and chemotherapies seem to have an impact on the immunological system and are responsible of a wide range of rare immunological side effects. Those are poorly described, due to the modif...

Eligibility Criteria

Inclusion

  • Case reported in the WHO's pharmacovigilance database till 02/01/2018
  • Adverse event reported were including the MedDRA terms for immune arthritis, systemic lupus erythematosus, hepatitis, rheumatoid arthritis and capillary leak syndrome.

Exclusion

  • Chronology not compatible between the drug and the toxicity

Key Trial Info

Start Date :

March 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 10 2018

Estimated Enrollment :

662 Patients enrolled

Trial Details

Trial ID

NCT03480529

Start Date

March 1 2018

End Date

March 10 2018

Last Update

September 4 2019

Active Locations (2)

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Page 1 of 1 (2 locations)

1

AP-HP, Pitié-Salpêtrière Hospital, Department of Pharmacology, CIC-1421, Pharmacovigilance Unit, INSERM.

Paris, France, 75013

2

Rhumatology department, CHU Strasbourg, Hautepierre hospital

Strasbourg, France, 67098