Status:

COMPLETED

Alcohol and Immune Response

Lead Sponsor:

Brown University

Conditions:

Alcohol Drinking

Alcohol; Harmful Use

Eligibility:

All Genders

21-55 years

Phase:

NA

Brief Summary

This study investigates how alcohol affects the immune system and behavior in healthy adults. The study also will examine how an individual's typical drinking habits may affect the immune system's res...

Eligibility Criteria

Inclusion

  • Ages 21-55 years
  • Able to speak and read English
  • Regular use of alcohol
  • Weight \> or = to 110 lbs and body mass index (BMI) in the 18.5-30 kg/m2 range
  • No self-reported use of drugs

Exclusion

  • Currently seeking treatment for alcohol or drug use
  • Chronic disease
  • Use of certain medications
  • GI disorders
  • Daily/near-daily use of NSAIDs
  • Positive urine test for certain drugs
  • History of withdrawal symptoms precipitated by alcohol abstinence
  • Clinical Institute Withdrawal Assessment for Alcohol score greater than or equal to 10
  • History of seizures
  • Current major psychiatric disorder
  • History of adverse reaction to standard blood draw
  • Inability to abstain from tobacco for 8 hours
  • Inability to abstain from cannabis for 48 hours
  • Pregnant, breastfeeding, or may become pregnant

Key Trial Info

Start Date :

October 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 18 2021

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT03483389

Start Date

October 1 2018

End Date

June 18 2021

Last Update

July 27 2021

Active Locations (1)

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1

Brown University

Providence, Rhode Island, United States, 02912

Alcohol and Immune Response | DecenTrialz