Status:
COMPLETED
The China Valvular Heart Disease Study
Lead Sponsor:
China National Center for Cardiovascular Diseases
Collaborating Sponsors:
Chinese Academy of Medical Sciences
Conditions:
Valvular Heart Disease
Eligibility:
All Genders
18+ years
Brief Summary
This is a observational、multicenter, prospective cohort study for adults with significant VHD. The purposes of this study were to evaluate the etiology、clinical characteristics、treatment modalities, a...
Eligibility Criteria
Inclusion
- patients over 60 years old meet one of the following conditions.
- moderate or above valvular heart disease as defined by echocardiography: （1）aortic stenosis, moderate or above, or valve area ≤1.5cm2, or maximal jet velocity ≥3.0m/sec, or mean pressure gradient ≥20mmHg, （2）aortic regurgitation, moderate or above, or jet width ≥25% of left ventricular outflow tract, or regurgitant volume ≥30ml/beat, or regurgitant fraction ≥30%, （3）mitral stenosis, moderate or above, or valve area ≤1.5cm2, （4）mitral regurgitation, moderate or above, or effective regurgitant orifice ≥0.2cm2, or regurgitant volume ≥30ml/beat, or regurgitant fraction ≥30%, （5）tricuspid stenosis, moderate or above, or valve area ≤1.0cm2, （6）tricuspid regurgitation, moderate or above, or central jet area ≥5.0cm2, （7）pulmonic stenosis, moderate or above, or maximal jet velocity \>4m/sec, （8）pulmonic regurgitation, moderate or above,
- or patients who had undergone any operation on a cardiac valve (percutaneous balloon commissurotomy, valve repair, valve replacement, transcatheter aortic valve implantation),
- or diagnosis of endocarditis as assessed by Duke criteria.
Exclusion
- Patients cannot be followed up for any reasons. Patients have been enrolled in this study.
Key Trial Info
Start Date :
April 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2020
Estimated Enrollment :
13917 Patients enrolled
Trial Details
Trial ID
NCT03484806
Start Date
April 1 2018
End Date
October 1 2020
Last Update
April 13 2022
Active Locations (1)
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1
Fuwai Hospital, National Center for Cardiovascular Diseases，Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100037