Status:

UNKNOWN

Simultaneous PET/MR Imaging of Human Brain Plasticity

Lead Sponsor:

Rupert Lanzenberger

Conditions:

Neuronal Plasticity

Eligibility:

All Genders

21-30 years

Phase:

NA

Brief Summary

Background: Neuronal plasticity is the brain's ability to continuously adapt to experiences and learning of new skills. Although this affects multiple characteristics of the brain such as structure, f...

Detailed Description

Methodological details: Each subject will undergo two PET/MR examinations. Imaging will include PET as well as acquisition of structural and functional MRI. Task-specific glucose metabolism will be qu...

Eligibility Criteria

Inclusion

  • Age range 21-30 years
  • Right-handedness
  • Willingness and competence to sign the informed consent form

Exclusion

  • History of or current physical, neurological or psychiatric disorder
  • History of or current substance abuse or medication including antipsychotic, antidepressant and antianxiety agents
  • Pregnancy or current breastfeeding
  • Contraindications for MRI-scanning (e.g., metal implants, steel grafts, etc), including dental implants causing signal artifacts
  • For subjects participating in earlier studies using ionizing radiation, the total radiation exposure of 30mSv over the last 10 years must not be exceeded, as specified in the Austrian legislation on radiation protection
  • Regular players of the video game Tetris (3 years before scanning).
  • Failure to comply with the study protocol or to follow the instructions of the investigating team

Key Trial Info

Start Date :

May 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03485066

Start Date

May 1 2017

End Date

November 1 2020

Last Update

September 23 2019

Active Locations (1)

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1

Department of Psychiatry and Psychotherapy, Medical University of Vienna

Vienna, Austria