Status:

COMPLETED

Substance Misuse To Psychosis for Ketamine (SToP-K)

Lead Sponsor:

The University of Hong Kong

Conditions:

Ketamine Abuse

Psychotic Disorders

Eligibility:

All Genders

12-65 years

Brief Summary

Evidence suggests that repeated or chronic ketamine use, as compared to acute ketamine users, posed a higher clinical risk of developing psychotic disorders, potentially related to the underlying chro...

Eligibility Criteria

Inclusion

  • Age: 12 - 65 years old
  • Able to read and communicate in English and/or Chinese
  • Able to give informed consent
  • Self-reported to have psychoactive substance use continuously for ≥3 month
  • At least one positive urine toxicology result showing the reported psychoactive substance being used

Exclusion

  • Age \<12 years old
  • Unable to read English or Chinese
  • Unable to give informed consent
  • Had been diagnosed to have Intellectual Disabilities (DSM-5) or Mental Retardation (ICD-10, F70-73)
  • Had been diagnosed to have primary psychosis prior to the use of any psychoactive substances, including alcohol
  • Had been diagnosed to have "bipolar and related disorder" prior to the use of any psychoactive substances, including alcohol
  • Had been diagnosed to have "major depressive disorder with psychotic features" prior to the use of any psychoactive substances, including alcohol
  • Had been diagnosed to have "psychotic disorder due to another medical condition" (DMS-5)
  • Self-reported to have abstained from any psychoactive substance use continuously for ≥12 months AND with negative urine toxicology result at the time of recruitment/ intake at the psychiatric services as recorded on case notes

Key Trial Info

Start Date :

June 12 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2020

Estimated Enrollment :

162 Patients enrolled

Trial Details

Trial ID

NCT03485339

Start Date

June 12 2018

End Date

April 1 2020

Last Update

July 31 2020

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Queen Mary Hospital

Hong Kong, Hong Kong, 000000

2

Western Psychiatric Centre

Hong Kong, Hong Kong, 00000