Status:
COMPLETED
Acute Exercise Effects in Obese Pregnancy
Lead Sponsor:
Duke University
Conditions:
Pregnancy Complications
Obesity
Eligibility:
FEMALE
18-40 years
Phase:
NA
Brief Summary
Obesity before and during pregnancy is associated with a higher risk for a number of obstetric and metabolic complications in women and their offspring. Of particular importance, obese women have a hi...
Detailed Description
Maternal obesity prevalence is at a historic high with over 1 in 3 women entering pregnancy obese and 1 in 10 extremely obese. Obesity before and during pregnancy is associated with a higher risk for ...
Eligibility Criteria
Inclusion
- First trimester BMI ≥ 30.0 and \<45.0 kg/m2 (calculated from clinical weight and height)
- Singleton gestation, between 23 weeks and 0/7 days and 28 weeks and 0/7 days
- Normal fetal anatomy (no major structural abnormalities identified on standard of care survey before enrollment)
- Established prenatal care at Women's Health Clinic before 18 weeks of gestation, plans to deliver at Barnes-Jewish Hospital
- Permission from Obstetrics physician provider to participate in study.
Exclusion
- Gestational or pre-gestational diabetes diagnosis
- Inability to provide voluntary consent
- Currently using illegal drugs (e.g., cocaine, methamphetamine, opiates) (safety risk and potential confounding)
- Current smoker who does not agree to stop (confounding)
- Participation in routine (\>1x/week) exercise program (may improve glucose metabolism/vascular function)
- History of heart disease, orthopedic, metabolic or neurological condition that would contraindicate exercise (safety risk)
Key Trial Info
Start Date :
November 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2020
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03750695
Start Date
November 20 2018
End Date
March 31 2020
Last Update
July 16 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Washington University
St Louis, Missouri, United States, 63110