Status:

RECRUITING

Muscle Fiber Fragments for Improved Function of Rotator Cuff Musculature Following Rotator Cuff Repair

Lead Sponsor:

Wake Forest University Health Sciences

Conditions:

Rotator Cuff

Eligibility:

All Genders

40-80 years

Phase:

NA

Brief Summary

In this study, a chest muscle sample (biopsy) will be taken and the muscle fibers will be removed from the sample and made into smaller strands or fragments. During this same procedure, those muscle f...

Detailed Description

Muscle fiber fragment (MFF) therapy has shown pre-clinical and clinical promise in the treatment of bladder neck insufficiency/incompetent outlet. Fragmentation of muscle fibers derived from autologou...

Eligibility Criteria

Inclusion

  • Males and females, ages 40 to 80 years
  • Unilateral Disease
  • \< 1.5cm tear

Exclusion

  • Diabetes
  • Peripheral Neuropathy
  • Previous Shoulder Surgery
  • Pain Syndrome; cuff arthroplasty
  • Major co-morbidities including, but not limited to, uncontrolled diabetes, cardiovascular, pulmonary, GI, coagulopathies
  • Arthritis of Shoulder
  • Unwilling or unable to comply with post-operative instructions or follow-up visits
  • Auto Immune Disease
  • Complete Subscapularis Tear
  • Teres Minor involvement
  • History of testing positive for HIV, Hep B, Hep C, HTLV-1, HTLV-2
  • Pregnancy
  • Implanted devices containing ferromagnetic material
  • Any implanted electrical stimulation devices (i.e. cochlear implant, defibrillator)
  • Any other condition which the PI feels would be not in the best interest for the patient or the study

Key Trial Info

Start Date :

November 4 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03752034

Start Date

November 4 2019

End Date

December 1 2026

Last Update

December 22 2025

Active Locations (1)

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Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States, 27157

Muscle Fiber Fragments for Improved Function of Rotator Cuff Musculature Following Rotator Cuff Repair | DecenTrialz