Status:
COMPLETED
Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Calcium Oxalate Urolithiasis
Eligibility:
All Genders
19-65 years
Phase:
NA
Brief Summary
The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of healthy participants ...
Detailed Description
Adults that are not colonized with O. formigenes, have no history of stone disease, and are in good health as judged by their medical history and a complete metabolic profile of their serum, will be r...
Eligibility Criteria
Inclusion
- Good health as judged from a medical history and reported medications
- Not colonized with O. formigenes
Exclusion
- History of any hepatic, renal, bowel or endocrine disease or any other condition that may influence the absorption, transport or urinary excretion of ions, which will compromise the interpretation of results
- colonized with O. formigenes
- abnormal urine chemistries or blood metabolic profiles
Key Trial Info
Start Date :
April 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 22 2025
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03752684
Start Date
April 2 2018
End Date
May 22 2025
Last Update
June 10 2025
Active Locations (1)
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1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294