Status:
COMPLETED
Influence of Periodontal Disease Treatment on Serum Levels of Sirtuin 1 and Mannose-binding Lectin
Lead Sponsor:
InCor Heart Institute
Conditions:
Periodontal Diseases
Eligibility:
All Genders
45+ years
Phase:
NA
Brief Summary
The premise of the relationship between the atherosclerotic process of coronary artery disease and periodontal disease is the immunoinflammatory process, which causes a significant increase in serum c...
Detailed Description
Inclusion criteria for PD were: presence of at least 15 teeth and clinical diagnosis of PD. Excluding third molars. This diagnosis was confirmed by the presence of at least 6 teeth with at least one n...
Eligibility Criteria
Inclusion
- Presence of installed periodontal disease.
- More than 15 teeth in the mouth
Exclusion
- uncontrolled diabetic,
- dialytic,
- smokers,
- patients with HIV and Hepatitis B and C.
- Pregnant subjects,
- edentulous patients,
- orthodontic brachytherapy were excluded from the study,
- patients using specific drugs known to affect periodontal tissues,
- patients who have undergone previous periodontal treatment (minimum of 6 months), \* patients taking anti-inflammatory drugs and corticosteroids.
Key Trial Info
Start Date :
October 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2018
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03753451
Start Date
October 1 2016
End Date
October 1 2018
Last Update
November 27 2018
Active Locations (2)
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1
INCOR- Heart Institute
São Paulo, São Paulo, Brazil, 05403900
2
INCOR - Heart Institute
São Paulo, Brazil, 05403-900