Status:
COMPLETED
The Role of Functional Epigenetic Modifications in Peri-Implantitis
Lead Sponsor:
NYU College of Dentistry
Conditions:
Periimplantitis
Eligibility:
All Genders
20-90 years
Brief Summary
The aim of this pilot, exploratory, single blind clinical trial is to evaluate the epigenetic changes associated with peri-implantitis.
Detailed Description
Twenty patients will be voluntarily enrolled in two groups: 10 healthy participants, and 10 participants with peri-implantitis. Periodontal and peri-implant clinical and radiographic measurements, as ...
Eligibility Criteria
Inclusion
- General
- Subjects must have read, understood, and signed an informed consent form.
- Subjects must be 20-90 years of age.
- Subjects must be non-smokers or ex-smokers who have quit smoking for at least one year prior to enrollment in the study.
- Subjects must be in good general health as assessed by the Investigator.
- Healthy Periodontal Subjects
- In addition to the general inclusion criteria, a healthy periodontal subject must meet all of the following criteria:
- • Subjects show gingival health and no history of periodontitis, as described in the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
- Peri-implantitis Subjects
- In addition to the general inclusion criteria, a PIT subject must meet all of the following criteria:
- Subjects with implant-supported prosthesis/es in function for at least 12 months who had at least one implant diagnosed with peri-implantitis based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
- Subjects must be committed to the study and the required follow-up visits.
- Standard of care treatment of the diseased implant with PID will consist on open flap debridement (OFD).
Exclusion
- General
Key Trial Info
Start Date :
October 4 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 2 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03753464
Start Date
October 4 2018
End Date
July 2 2019
Last Update
July 3 2024
Active Locations (1)
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1
Bluestone Center for Clinical Research. New York University College of Dentistry
New York, New York, United States, 10010-4086