Status:
COMPLETED
Does Hyaluronic Acid Affect Periodontal Treatment?
Lead Sponsor:
Yuzuncu Yil University
Conditions:
Periodontitis
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
Objective: The aim of this study is to evaluate the effect of HA as an adjunct to scaling and root planning (SRP) on clinical parameters, periodontal inflamed surface area (PISA) and adenosine deamina...
Detailed Description
Design: A total of 24 Stage II-III periodontitis patients will be included in this split-mouth, randomized-controlled study. The study population will be divided into four groups: in Group 1 (SRP): SR...
Eligibility Criteria
Inclusion
- Systemically healthy
- moderate-to-severe periodontitis
- at least five sites with ≥5mm probing depth (PD)
- at least ≥20 teeth
- Stage II-III periodontitis according to the 2017 World Workshop
- Age between18-55
Exclusion
- receiving systemic or local antibiotics within the past six months
- prior surgical or non-surgical periodontal treatment within the past six months
- smoking
- pregnancy
- lactation
- age ≤18 years or ≥55 years
- hypertension
- known chronic systemic diseases (i.e., diabetes mellitus, rheumatoid arthritis), - - known hypersensitivity to one of the ingredients of the HA preparation.
Key Trial Info
Start Date :
August 30 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2018
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03754010
Start Date
August 30 2017
End Date
September 30 2018
Last Update
November 27 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Van Yuzuncu Yil University Faculty of Dentistry
Van, Turkey (Türkiye), 65080