Status:
COMPLETED
Sleep Extension and Insulin Sensitivity in Adolescents
Lead Sponsor:
Children's Hospital of Eastern Ontario
Conditions:
Sleep
Eligibility:
All Genders
13-18 years
Phase:
NA
Brief Summary
BACKGROUND: The influence of sleep extension on glucose homeostasis in adolescents at risk for type 2 diabetes is unknown. This issue is of high clinical relevance given the high prevalence of sleep d...
Eligibility Criteria
Inclusion
- Adolescents between the ages of 13 and 18 with obesity (body mass index greater than the 95th percentile) and dyslipidemia (total cholesterol ≥ 200 mg/dL; low-density lipoprotein cholesterol ≥ 130 mg/dL; non-high-density lipoprotein ≥ 145 mg/dL; triglycerides ≥ 130 mg/dL; and high-density lipoprotein \< 40 mg/dL)
- Adolescents who report between 6.5-8 hours of sleep per night will be eligible to ensure that adolescents can extend and restrict sleep duration without reaching a ceiling for what can be achieved (i.e. 8-10 hours/night of sleep is recommended at this age) while limiting excessive sleep deprivation
Exclusion
- History of a chronic medical or psychiatric condition
- Use of medications that could affect sleep or glucose homeostasis (e.g., metformin, thyroid medication, stimulant medication, etc.)
- History of sleep problems (e.g. sleep apnea).
Key Trial Info
Start Date :
January 5 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2021
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT03754036
Start Date
January 5 2019
End Date
December 12 2021
Last Update
July 19 2022
Active Locations (1)
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1
Children's Hospital of Eastern Ontario Research Institute
Ottawa, Ontario, Canada, K1H 8L1