Status:
COMPLETED
SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Aneurysmal Subarachnoid Hemorrhage
Headache
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Headache control is one of the major challenges in patients who suffered an acute aneurysmal subarachnoid hemorrhage (aSAH). Headache affects 90% of the patient and is resistant to the major pain medi...
Detailed Description
After aneurysmal subarachnoid hemorrhage (aSAH) almost 90 % of patients experience a severe headache during their hospital stay. Pain control often requires high doses of opioid drugs and sedation tha...
Eligibility Criteria
Inclusion
- Age \>18 years
- Low grade subarachnoid hemorrhage (WFNS score between 1 and 3)
- Aneurysmal rupture ≤ 5 days
- Ruptured aneurysm secured by coiling since at least 48 h
- Headache with a mean numeric verbal scale ≥ 4/10 during the last 24 hours
- No contraindication for lumbar puncture
- Affiliation to french social security
- Person able to express her consent and to assess own headache intensity
Exclusion
- Minor,
- Pregnancy, breastfeeding
- Subarachnoid hemorrhage without aneurysm
- Ruptured aneurysm not secured
- High grade (WFNS 4 and 5) subarachnoid hemorrhage
- Efficient anticoagulation
- External ventricular drain placed before randomisation
- People under legal protection
- Participation to another research study with an ongoing disqualification period
Key Trial Info
Start Date :
November 28 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2022
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT03754335
Start Date
November 28 2018
End Date
December 1 2022
Last Update
February 13 2023
Active Locations (1)
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1
University Hospital Toulouse
Toulouse, France, 31059