Status:

COMPLETED

Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Gastrointestinal Microbiota for Chinese Children With Crohn's Disease

Lead Sponsor:

Children's Hospital of Fudan University

Conditions:

Crohn Disease

Enteral Nutrition

Eligibility:

All Genders

1-17 years

Phase:

NA

Brief Summary

Inflammatory bowel diseases (IBD) are chronic inflammatory diseases. It is believed that the inflammation results from sustained abnormal immune response towards altered or pathogenic microbiota in ge...

Eligibility Criteria

Inclusion

  • Pediatric CD patients who were newly diagnosed and being treated with EEN at the Children's Hospital of Fudan University

Exclusion

  • (1) patients who were administered corticosteroids, immunosuppressive drugs, or biological agents prior to the study; (2) patients who could not finish the daily prescribed volume of formula for any reason; (3) patients who could not attend consecutive follow-up sessions; (4) patients who had received antibiotics or probiotics within 1.5 months prior to the study; and (5) patients who had been given corticosteroids, immunosuppressive drugs, biological agents, antibiotics, or probiotics during the EEN process.

Key Trial Info

Start Date :

February 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2019

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT03755583

Start Date

February 1 2017

End Date

December 31 2019

Last Update

January 27 2020

Active Locations (1)

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Children's hospital of Fudan university

Shanghai, Shanghai Municipality, China, 201102