Status:

UNKNOWN

The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis

Lead Sponsor:

Beijing University of Chinese Medicine

Collaborating Sponsors:

Beijing Hospital of Traditional Chinese Medicine

Conditions:

Mastitis Acute Female

Eligibility:

FEMALE

18-70 years

Phase:

PHASE2

PHASE3

Brief Summary

The object of the study is to evaluate the effect of Pugongying (Herba Taraxaci) Granules to reduce the application of antibiotics for women with acute mastitis.

Detailed Description

Acute mastitis affects the health and quality of life of the infants and mothers during the lactation. Increasing studies indicate that bacterial infections and/or dysbacteriosis are essential to the ...

Eligibility Criteria

Inclusion

  • Women in lactation who have strong willing to breastfeeding;
  • The course of acute mastitis should be within 3 days, and the ultrasound examination indicates there is no abscess cavity formed;
  • The body temperature is higher than 37.2°C but lower than 41°C;
  • The VAS scores of participants≥4;
  • Patients with acute mastitis have not received other medical therapies;
  • Those who have signed informed consent.

Exclusion

  • Participants who suffered nipple ulceration, painful fissuring or developmental defects fail to breastfeed;
  • Participants with other breast diseases are not appropriate to breastfeed;
  • Participants with severe cognitive or metabolic diseases will affect breastfeeding;
  • Participants who have been allergic to penicillin and cephalosporin.

Key Trial Info

Start Date :

December 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2021

Estimated Enrollment :

306 Patients enrolled

Trial Details

Trial ID

NCT03756324

Start Date

December 20 2018

End Date

March 31 2021

Last Update

July 7 2020

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Beijing Hospital of Traditional Chinese Medicine

Beijing, China

2

Beijing University of Chinese Medicine Third Affiliated Hospital

Beijing, China

3

Tongzhou Maternal & Child Health Hospital of Beijing

Beijing, China