Status:

COMPLETED

Cost Effectiveness of Prolotherapy Injections Prior to Total Knee Arthroplasty

Lead Sponsor:

Tokat State Hospital

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

50-70 years

Brief Summary

This study compared the cost effectiveness of two-stage algorithm (prolotherapy injections (PrT) combined with rehabilitation protocol (RP) prior to total knee arthroplasty (TKA)) and one-stage algori...

Detailed Description

The aim of the present study was to compare the cost effectiveness of two-stage algorithm (prolotherapy injections (PrT) combined with rehabilitation protocol (RP) prior to total knee arthroplasty (TK...

Eligibility Criteria

Inclusion

  • III and IV levels of knee osteoarthritis according to Kellgren-Lawrence
  • Had at least six months of symptoms resistant to at least three months of conservative methods (lifestyle modification, weight reduction, regular exercise, physiotherapy, non-steroidal anti-inflammatory drugs, intraarticular injection methods) -

Exclusion

  • With rheumatic diseases, immune diseases or other systemic inflammatory diseases
  • With active infection, osteomyelitis or history of chronic infection around knee joint
  • Had undergone previous operation on knee
  • Had bleeding tendency (hereditary or acquired)
  • Pregnant patients

Key Trial Info

Start Date :

January 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 24 2018

Estimated Enrollment :

197 Patients enrolled

Trial Details

Trial ID

NCT03758183

Start Date

January 1 2016

End Date

October 24 2018

Last Update

November 29 2018

Active Locations (1)

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1

Serkan Akpancar

Tokat Province, Turkey (Türkiye), 60060