Status:

UNKNOWN

The Influence of Gene Polymorphism on Clinical Outcomes in Patients Undergoing PCI

Lead Sponsor:

Beijing Anzhen Hospital

Conditions:

Antiplatelet Therapy

CYP2C19 Polymorphism

Eligibility:

All Genders

18+ years

Brief Summary

Dual antiplatelet therapy with aspirin and thienopyridines is an essential treatment in patients undergoing percutaneous coronary intervention (PCI). However, despite intensified antiplatelet treatmen...

Detailed Description

Patients undergoing PCI who received dual antiplatelet therapy with both aspirin (100mg) and P2Y12 inhibitors in standard dosage were enrolled. Investigators examined plasma biomarkers for platelet ac...

Eligibility Criteria

Inclusion

  • The patients undergoing PCI
  • More than 18 years old
  • Treated with aspirin and P2Y12 inhibitors (clopidogrel or ticagrelor)

Exclusion

  • Inability to provide written informed consent

Key Trial Info

Start Date :

December 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2021

Estimated Enrollment :

12000 Patients enrolled

Trial Details

Trial ID

NCT03758248

Start Date

December 1 2018

End Date

September 30 2021

Last Update

December 8 2020

Active Locations (1)

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Beijing Anzhen Hospital

Beijing, Beijing Municipality, China, 100029