Status:

WITHDRAWN

The Effect of Remote Ischemic Preconditioning on Ischemia/Reperfusion Injury in a Liver Transplant Recipient

Lead Sponsor:

Rigshospitalet, Denmark

Conditions:

Liver Transplant; Complications

Ischemia Reperfusion Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Ischemia and reperfusion injury is unavoidable during a liver transplantation. Remote ischemic preconditioning, a safe and feasible method, has previously been shown to reduce ischemia and reperfusion...

Detailed Description

Background The use of solid organ transplantation, including liver transplantation, is the golden standard for many end-stage solid organ diseases. Ischemia and reperfusion injury is unavoidable durin...

Eligibility Criteria

Inclusion

  • Patients undergoing liver transplantation
  • Patients aged 18 or above
  • Patients who have given an informed consent

Exclusion

  • Patients undergoing re-transplantation.
  • Patients who do not or cannot give an informed consent.
  • Patients who have undergone surgery six weeks prior to liver transplantation.
  • Patients with known peripheral vascular disease.
  • Patients with an infection localized to the area of rIC-intervention
  • Patients with at a high risk or with previous history of multiple thrombo-embolic diseases.
  • Patients undergoing active immunosuppressive therapy

Key Trial Info

Start Date :

April 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2022

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03758352

Start Date

April 1 2020

End Date

November 1 2022

Last Update

October 8 2020

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