Status:

COMPLETED

Association of Mean Platelet Volume and Cardiovascular Disease in Children With End Stage Renal Disease.

Lead Sponsor:

Isfahan University of Medical Sciences

Conditions:

Cardiovascular Diseases

Carotid Intimal Media Thickness

Eligibility:

All Genders

Up to 18 years

Brief Summary

Cardiovascular disease (CVD) is the major risk factor for death in end stage renal diseases (ESRD). Approximately 80% of ESRD patients have some degrees of left ventricular abnormalities at initiation...

Eligibility Criteria

Inclusion

  • Children under 18 years who have being dialyzed (hemodialysis or peritoneal dialysis) regularly more than 6 months, as case group.
  • Age and gender matched healthy children who have been referred for routine medical examination.

Exclusion

  • Patients with uncontrolled hypertension (until being stabled)
  • Patients on any kind of antithrombotic agents or NSAIDs
  • Severe obesity
  • Diabetes patients
  • Patients with a past history of CVD or stroke in the last 6 months
  • Passive smokers who contacted daily with high smokers in their houses
  • Patients with known hematologic diseases or malignancies (such as Fanconi Anemia)
  • Uncontrolled hypothyroid or hyperthyroid patients
  • Patients with recent (in the last 4 weeks) catheter or exit -site infection.

Key Trial Info

Start Date :

February 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 15 2018

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT03759002

Start Date

February 1 2016

End Date

June 15 2018

Last Update

November 29 2018

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