Status:

COMPLETED

Method of Clopidogrel Pre-treatment Undergoing Conventional Coronary Angiogram in Angina Patients

Lead Sponsor:

Korea University Anam Hospital

Conditions:

Angina, Stable

Eligibility:

All Genders

20+ years

Phase:

NA

Brief Summary

The study included 511 patients who underwent PCI because of angina during 2010-2011 at three Korean hospitals. Clopidogrel-naïve patients received either a loading dose (LD; 600 mg at 2-24 h before t...

Detailed Description

Elevation of myocardial infarction markers after coronary stenting reflects periprocedural myonecrosis or periprocedural myocardial infarction (PMI), which is associated with an increase in cardiac ev...

Eligibility Criteria

Inclusion

  • Written informed consent and, stable angina pectoris and, at least 1 ischemic evidence below
  • Treadmil test positive
  • ST-T change in resting ECG or 24-hour ECG
  • Regional wall motion abnormality in Echocardiography or cardiac MRI
  • Myocardial ischemia at MIBI scan
  • moderate to severe stenosis at coronary CT angiography
  • chest pain or dyspnea

Exclusion

  • AST or ALT \> 3 times upper normal limits
  • Serum creatinine \> 2.0 mg/dL
  • chronic malaborption status (disorder or operation)
  • planned surgery within 1 year
  • pregnancy or breast-feeding patients
  • life expectancy \< 1 year

Key Trial Info

Start Date :

October 18 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2013

Estimated Enrollment :

511 Patients enrolled

Trial Details

Trial ID

NCT03759067

Start Date

October 18 2010

End Date

July 31 2013

Last Update

November 29 2018

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