Status:
COMPLETED
Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy
Lead Sponsor:
Ain Shams University
Conditions:
Iron Deficiency Anemia
Eligibility:
FEMALE
18-38 years
Phase:
PHASE2
Brief Summary
The main drawbacks with oral iron are side-effects, poor compliance, and limited absorption from the gut. It has become very apparent gastrointestinal intolerance with oral iron therapy is dose relate...
Eligibility Criteria
Inclusion
- Pregnant women with single fetus.
- Second trimester (14-20weeks of gestation).
- Normal Hemoglobin level: more than10g\\dl.
- Serum ferritin less than 15 mcg / L
Exclusion
- Other type than iron-deficiency anemia (thalassemia, hemolytic anemia … etc.)
- Any other chronic diseases (bronchial asthma, renal or hepatic, hematological or cardiovascular diseases … etc.)
- Having hypersensitivity to iron preparations.
- Treatment with any other iron preparation in the last month.
- History of peptic ulcer, oesophagitis or hiatal hernia.
- Medical disorders with pregnancy.
- Need for alternative parenteral route to blood transfusion when rapid increase is required (perioperative anemia-severe anemia in late pregnancy-postpartum anemia) .
- Bleeding in early pregnancy.
- Refusal to participate in the study.
- Family history of thalassemia-sickle cell anemia or malabsorption syndrome.
- Recent blood transfusion.
- Inflammatory bowel disease as intolerance of oral therapy but tolerated to parenteral route.
Key Trial Info
Start Date :
January 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 20 2018
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT03759353
Start Date
January 15 2018
End Date
November 20 2018
Last Update
November 30 2018
Active Locations (1)
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1
Ain SHams Maternity Hospital
Cairo, Abbaseya, Egypt, 002