Status:

UNKNOWN

IPS Differentiated Cardiomyocytes Vein Transplantation for Chronic Heart Failure

Lead Sponsor:

Beijing University of Chinese Medicine

Collaborating Sponsors:

Dongzhimen Hospital, Beijing

Conditions:

Chronic Heart Failure

Eligibility:

All Genders

30-80 years

Phase:

PHASE2

PHASE3

Brief Summary

Based on the safety evaluation of primates, the best cell transplantation scheme was integrated. One patient with CHF caused by coronary heart disease, one patient with CHF caused by dilatation and on...

Eligibility Criteria

Inclusion

  • It accords with the diagnostic standard of chronic heart failure.
  • The etiological diagnosis accords with the corresponding diagnostic standard.
  • The age is 30\~80 years old.
  • Cardiac function classification is III- grade IV.
  • Signed informed consent.

Exclusion

  • Those who did not meet the diagnostic criteria and were included in the standard.
  • Patients with severe dyspnea (such as COPD with pulmonary encephalopathy, upper gastrointestinal bleeding, etc.) accompanied by obvious hypoxemia and hemodynamic instability.
  • Patients with severe primary diseases, such as liver and kidney diseases, hematological diseases, autoimmune diseases, malignant tumors, progressive diseases or diseases with poor prognosis, such as severe infection, severe water and electrolyte disorders, acid-base imbalance.
  • Various infectious diseases.
  • Participants in other clinical trials in the past two months.

Key Trial Info

Start Date :

December 31 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT03759405

Start Date

December 31 2022

End Date

December 31 2024

Last Update

July 22 2022

Active Locations (1)

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Beijing University of Chinese Medicine

Beijing, Beijing Municipality, China, 100029