Status:

COMPLETED

The Risk of Hypertension Associated With Oral Glucocorticoids in Chronic Inflammatory Diseases

Lead Sponsor:

University of Leeds

Conditions:

Hypertension

Eligibility:

All Genders

18+ years

Brief Summary

Glucocorticoids are widely used for the treatment of chronic inflammatory diseases. In 2008, it was estimated that 0.8% of the United Kingdom adult population had used long-term (≥ 3 months) glucocort...

Detailed Description

Hypertension is a chronic condition which affects 1 in 5 of the world adult population. The cause of hypertension is unknown in about 95% of patients, whilst 5% are secondary to underlying adrenal dis...

Eligibility Criteria

Inclusion

  • Patients aged 18 years old or over
  • Registered in a participating general practice 1 year or more during the study period
  • Minimum of 1 year prior to study entry meeting CPRD data quality
  • Diagnosed with at least one of the 6 chronic inflammatory diseases

Exclusion

  • Patients aged under 18 years during the study period
  • Registered in general practices that did not consent to data linkage

Key Trial Info

Start Date :

January 1 1998

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2015

Estimated Enrollment :

111804 Patients enrolled

Trial Details

Trial ID

NCT03760562

Start Date

January 1 1998

End Date

September 30 2015

Last Update

November 30 2018

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