Status:
COMPLETED
Comparison of Hyaluronic Acid and Platelet-rich Plasma Injections
Lead Sponsor:
Bezmialem Vakif University
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
This study aims to compare the effects of hyaluronic acid injection and platelet rich plasma injection in terms of pain, physical function and femoral cartilage thickness in short term treatment in pa...
Detailed Description
Platelet-rich plasma and hyaluronic acid injections are both popular treatments and commonly used for treatment of knee osteoarthritis. Even though there are many studies investigating the effectivene...
Eligibility Criteria
Inclusion
- Subject is able to consent
- Subject meets Osteoarthritis Research Society International (OARSI) criteria for knee osteoarthritis
- Subject has radiographic Kellgren-Lawrence grade 2-3 osteoarthritis
- Unilateral osteoarthritis/complaint
Exclusion
- Past or actual knee infection
- History of surgery, fracture on knee
- Collagen tissue disease
- Systemic inflammatory disease (rheumatoid arthritis, spondyloarthritis etc.)
- Systemic diseases (diabetes, hematologic diseases, endocrinopathies, renal failure, liver failure)
- Knee injection in past 6 months
- Immunodeficiency
- Pregnant/breastfeeding
- Malignancy
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 13 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03761472
Start Date
January 1 2019
End Date
January 13 2020
Last Update
January 18 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Bezmialem Vakif University
Istanbul, Fatih, Turkey (Türkiye), 34093