Status:
UNKNOWN
Nicardipine and Labetalol Effects on Cerebral Hemodynamics in Preeclampsia
Lead Sponsor:
Hopital Antoine Beclere
Conditions:
Preeclampsia Severe
Eligibility:
FEMALE
18+ years
Brief Summary
Realization of transcranial doppler and optic nerve sheath in severe preeclamptic patients to evaluate the impact of nicardipine and labetalol on cerebral hemodynamics.
Eligibility Criteria
Inclusion
- Aged up to 18 years
- patient with severe preeclampsia defined by Systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg after 20 weeks of amenorrhea, associated with neurologic troubles, eclampsia of epigastric pain.
- Decision by clinician to introduce an antihypertensive therapy by oral route : either labetalol or nicardipine
Exclusion
- history of intracranial expansive processus, surgery or vascular disease
- infectious state on probe placement
- unilateral anophthalmia
Key Trial Info
Start Date :
November 29 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03761888
Start Date
November 29 2018
End Date
May 1 2019
Last Update
December 3 2018
Active Locations (1)
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1
Hôpital Béclère
Clamart, France, 92140