Status:
COMPLETED
Dialysis Weaning in Intensive Care Units (Dialysis STOP)
Lead Sponsor:
Dr Alexandre Gros
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
18+ years
Brief Summary
Evaluation of daily urinary urea excretion, to guide Renal Replacement Therapy weaning, in Intensive Care Units. The objective is to show that remove the dialysis catheter, once daily urinary urea ex...
Detailed Description
Daily urinary excretion of urea may provide a safe and reproducible renal replacement therapy withdrawal criterion, according to a recent French study (citations). A rate greater than 1.35 mmol/kg/d w...
Eligibility Criteria
Inclusion
- All patients \> 18 of age, who have a Renal Replacement Therapy, in intensive care unit,
- with a diuresis \> 100 ml/d.
Exclusion
- Patients still presenting "hard" criteria for RRT: metabolic acidosis with pH \< 7.15 and PCO2 \<50mmHg; acute pulmonary edema (\> 5l 02 or 50% FiO2 for Sp02 \> 95%) objectified by echocardiography; K\> 5.5 mmol/l after treatment
- Renal transplantation
- Long-term chronic kidney injury or short-term dialysis project (arteriovenous fistula created).
- Acute Kidney Injury secondary to thrombotic microangiopathy
- Acute Kidney Injury secondary to an obstacle even if dialysed
- RRT started for toxic cause without IRA (lithium,...)
Key Trial Info
Start Date :
September 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2019
Estimated Enrollment :
260 Patients enrolled
Trial Details
Trial ID
NCT03763188
Start Date
September 1 2016
End Date
September 1 2019
Last Update
March 17 2020
Active Locations (1)
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1
Alexandre Gros
Bordeaux, Aquitaine, France, 33000